HISTORY AND HUMANITIES IN DERMATOLOGY Darwinian Medicine and Psoriasis
نویسنده
چکیده
Darwinian medicine, or evolutionary medicine, regards some pathological conditions as attempts by the organism to solve a problem or develop defense mechanisms. At certain stages of human evolution, some diseases may have conferred a selective advantage. Psoriasis is a high-penetrance multigenic disorder with prevalence among whites of up to 3%. Psoriatic lesions have been linked with enhanced wound-healing qualities and greater capacity to fight infection. Leprosy, tuberculosis, and infections caused by viruses similar to human immuno-deficiency virus have been postulated as environmental stressors that may have selected for psoriasis-promoting genes in some human populations. The tendency of patients with severe psoriasis to develop metabolic syndrome may reflect the body's attempt to react to environmental stresses and warning signs by triggering insulin resistance and fat storage. alarma que desencadenan resistencia insulínica y ahorro de grasa. Documento descargado de http://www.actasdermo.org el 03/04/2017. Copia para uso personal, se prohíbe la transmisión de este documento por cualquier medio o formato.
منابع مشابه
The Worldviews of Stephen Jay
The Academic Nature of Worldviews ................................................................................ 1 Pre-Darwinian Worldviews ................................................................................................ 2 Darwin’s Worldview ........................................................................................................... 5 Mendel, Population Genetics...
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تاریخ انتشار 2015